Could implant choice significantly change breast reconstruction outcomes after postmastectomy radiotherapy?
9.3 %
Fewer surgical revisions for capsular contracture
versus 25.7 %significantly fewer surgical revisions for capsular contracture than non-polyurethane implants
- Patients
- 1455
- PRExRT Cohort Study
- Retrospective
Take-home
Use of prepectoral polyurethane coated implants in the setting of radiotherapy: the OPBC-09 PRExRT retrospective cohort study
The international PRExRT study evaluated 1,455 patients undergoing prepectoral implant-based breast reconstruction followed by radiotherapy.
Polyurethane-coated implants were associated with significantly fewer surgical revisions for capsular contracture than non-polyurethane implants (9.3% vs. 25.7%).
They were also associated with lower rates of major infection, implant loss, reoperation and implant rotation.
These findings suggest polyurethane-coated implants may offer important advantages in postmastectomy radiotherapy, although prospective validation is needed.
